Lack of association between transforming growth factor-beta 1 gene polymorphisms and mitral valve prolapse in Taiwan Chinese

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 台中附設醫院 > 期刊論文 > Item 310903500/29036

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题名:	Lack of association between transforming growth factor-beta 1 gene polymorphisms and mitral valve prolapse in Taiwan Chinese
作者:	Chou, HT;Shi, YR;Hsu, Y;Tsai, FJ
贡献者:	附設醫院內科部心臟科;China Med Coll Hosp, Dept Med, Div Cardiol, Taichung 404, Taiwan;China Med Coll Hosp, Dept Pediat Med Res & Med Genet, Taichung 404, Taiwan
日期:	2002
上传时间:	2010-09-24 14:19:23 (UTC+8)
出版者:	I C R PUBLISHERS
摘要:	Objective: Assisted hatching may enhance embryo implantation. This study was conducted to examine the efficacy of the laser- and chemical-assisted hatching for promotion of implantation (IR), pregnancy (PR). and delivery rate (DR) in older women undergoing IVF cycles. Design: Prospective study. Setting: An IVF unit of a medical center. Patient(s): A total of 601 embryos from 141 women aged greater than or equal to38 years underwent controlled ovarian hyperstimulation (COH) and assisted hatching. Intervention(s): The study population was divided into two groups: group I had laser-assisted hatching (n = 85) and group 2 had chemical-assisted hatching (n = 56). Before the transfer, the day 3 embryos were hatched by using a 1.48-mum noncontact diode laser or acid Tyrode's solution. Main Outcome Measurement(s): The IR, PR, and DR between the groups were compared. Result(s): There were no statistical differences between groups in age, E-2 concentrations during hCG administration, gonadotrophin dosage, embryo grade, the numbers of oocytes retrieved, oocytes fertilized, and embryos transferred. Higher IR, PR, and DR were noted in the laser-assisted hatching group. The IR, PR. and DR were: group 1, 8.2%/31.8%/24.7% and group 2, 3.8%/16.1%/10.7%, respectively. Conclusion(s): Laser-assisted hatching of embryos is more effective than the chemical method in enhancing the IR and PR of women with advanced age. The laser system allows an easier, faster, and safer micromanipulation of the zona pellucida, which provided a better method in zona drilling. (C) 2002 by American Society for Reproductive Medicine.
關聯:	JOURNAL OF HEART VALVE DISEASE 11(4):478-484
显示于类别:	[台中附設醫院] 期刊論文

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