Transcatheter closure of patent ductus arteriosus using Gianturco coils in adolescents and adults

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Title:	Transcatheter closure of patent ductus arteriosus using Gianturco coils in adolescents and adults
Authors:	Wang, JK;Liau, CS;Huang, JJ;Hsu, KL;Lo, PH;Hung, JS;Wu, MH;Lee, YT
Contributors:	附設醫院內科部;Natl Taiwan Univ Hosp, Dept Pediat, Taipei, Taiwan;Natl Taiwan Univ Hosp, Dept Internal Med, Taipei, Taiwan;China Med Coll Hosp, Dept Internal Med, Taichung, Taiwan
Date:	2002
Issue Date:	2010-09-24 14:18:45 (UTC+8)
Publisher:	WILEY-LISS
Abstract:	Levels of sister chromatid exchanges (SCEs), high-SCE frequency cells (HFCs), DNA-protein cross-links (DPCs), blood lead (BLL), and zinc protoporphyrin (ZPP) were measured in peripheral blood from three groups. The lead workers were divided into two groups: a high BLL group (greater than or equal to15 mug/dl) and a low BLL group (<15 mug/dl). The control subjects were selected from an area that bad not been contaminated with lead and had normal BLL and ZPP levels. In addition, exposure to airborne lead was measured for 11 lead workers, and the time-weighted average was shown to range from 0.19 to 10.32 mg/m(3). The BLL levels of 9 of 11 workers were >15 mug/dl, of which, 3 exceeded current exposure limits (greater than or equal to40 mug/dl). The BLL levels of all 11 controls were <15 mug/dl. The average SCE and DPC values for the workers were 6.1 SCEs/cell and 1.9%, which were significantly higher (P < 0.01, Wilcoxon's test) than the value of 5.2 SCEs/cell and 1.1% for the control subjects. Lead workers had significantly higher BLL and ZPP levels than did the controls. Statistically significant increases in DPCs, SCEs, and HFCs were observed for the high-BLL group compared with the control group. The results of this study suggest that DPCs, SCEs, and HFCs are reliable biomarkers for monitoring workers exposed to lead and clearly indicate health effects from occupational exposure to lead.
Relation:	CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS 55(4):513-518
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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