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    題名: Gastrodia elata BL mediates the suppression of nNOS and microglia activation to protect against neuronal damage in kainic acid-treated rats
    作者: Hsieh, CL;Chen, CL;Tang, NY;Chuang, CM;Hsieh, CT;Chiang, SY;Lin, JG;Hsu, SF
    貢獻者: 附設醫院中醫部;China Med Univ Hosp, Dept Chinese Med, Taichung, Taiwan;China Med Univ Hosp, Dept Emergency, Taichung, Taiwan;China Med Univ, Grad Inst Integrat Chinese & Western Med, Taichung, Taiwan;China Med Univ, Coll Chinese Med, Sch Chinese Med, Taichung 404, Taiwan;China Med Univ, Coll Chinese Med, Sch Chinese Med, Taichung 404, Taiwan;China Med Univ, Grad Inst Chinese Med Sci, Coll Chinese Med, Taichung, Taiwan;China Med Univ, Acupuncture Res Ctr, Taichung, Taiwan;Taipei Med Univ, Dept Pathol, Taipei, Taiwan;Jen Ai Hosp, Dept Internal Med, Taichung, Taiwan
    日期: 2005
    上傳時間: 2010-09-24 14:17:52 (UTC+8)
    出版者: WORLD SCIENTIFIC PUBL CO PTE LTD
    摘要: OBJECTIVE: To undertake cost-utility analysis for tympanomastoid surgery to analyze itscost-effectiveness in treating adult chronic suppurative otitis media (CSOM). METHODS: Seventy-seven patients with CSOM were evaluated with the Chronic Ear Survey (CES) before and 1 year after tympanomastoid surgery. Direct health care cost data during the 1st year after operation were retrieved. The utility gain was defined as change in the CES total score. The cost-utility ratio (CUR) was defined as cost per utility gain. Patients were stratified by disease type into wet-ear and dry-ear groups. RESULTS: The average total direct cost attributable to tympanomastoid surgery is (in New Taiwan dollars [NT$]) 45,716.3 in the 1st postoperative year, and the average CUR is NT$ 1850.9. The lower CUR of NT$ 1280.9 for the wet-ear group is due to the greater utility gain (37.6 +/- 3.4 versus 24.4 +/- 6.8, P < 0.05) despite its higher cost (NT$ 48,163.2 versus NT$ 38,419.7, P < 0.05). CONCLUSIONS: Treating continuously or intermittently draining ears is more cost-effective, as compared with managing a quiescent infection, because of its favorable utility gain. (C) 2005 American Academy of Otolaryngology.
    關聯: AMERICAN JOURNAL OF CHINESE MEDICINE 33(4):599-611
    顯示於類別:[台中附設醫院] 期刊論文

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