中國醫藥大學機構典藏 China Medical University Repository, Taiwan:Item 310903500/28948
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    題名: Transorbital penetrating injury of the paranasal sinuses
    作者: Wu, MR;Shih, CT;Yeh, CW
    貢獻者: 附設醫院;Taipei Municipal Jen Ai Hosp, Dept Otolaryngol, Taipei, Taiwan;China Med Coll Hosp, Taichung, Taiwan
    日期: 1998
    上傳時間: 2010-09-24 14:16:46 (UTC+8)
    出版者: HEADLEY BROTHERS LTD
    摘要: This study was designed to study the in vivo prevalence and the heterogeneity of H.pylori in patients with gastroduodenal diseases in central Taiwan. H. pylori infection was detected in 74.1% (575/776) of the symptomatic population studied. The prevalence of H. pylori infection increased from 11.1% in those between the ages of one to 20, to 82.9% in those between the ages of 41 and 50, and to 84% in those between the ages of 51 and 60. There was no significant difference in the prevalence of H pylori infection between men and women. Among different blood types, the prevalence and relative risk of H. pylori infection was significantly higher in blood group O patients (90.3%) than in blood group A (41%), blood group B (27.4%), or blood group AB (62%) patients. Metronidazole resistance was found in 6.7% of the primary isolates. The prevalence of metronidazole-resistant H. pylori strains was higher in women (7.69%) than in men (6.25%), but this difference was not significant. A total of 88% of H. pylori strains were cagA-positive. CagA gene-positive strains were present in 90.1% of duodenal ulcers, 90% of duodenal ulcers combined with gastric ulcer, 85.8% of gastric ulcers, and 69.2% of gastritis patients, and was significantly higher in peptic ulcer disease groups than in the gastritis group. In conclusion, there was a low incidence (6.7%) of metronidazole-resistant H pylori strains and a high prevalence (88%) of H. pylori cagA-positive strains in central Taiwan. This study also demonstrated a significant in vivo correlation between active H. pylori infection and blood group O-positive patients, and showed a significant association between cagA gene-positive H. pylori strains and the development of peptic ulcers.
    關聯: JOURNAL OF LARYNGOLOGY AND OTOLOGY 112(12):1202-1204
    顯示於類別:[台中附設醫院] 期刊論文

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