中國醫藥大學機構典藏 China Medical University Repository, Taiwan:Item 310903500/28901
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    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.cmu.edu.tw/ir/handle/310903500/28901


    题名: Relationship between blood lead levels and renal function in lead battery workers
    作者: Wang, VS;Lee, MT;Chiou, JY;Guu, CF;Wu, CC;Wu, TN;Lai, JS
    贡献者: 公共衛生學院職安系;China Med Coll, Dept Occupat Safety & Hlth, Taichung, Taiwan;Taiwan Prov Inst Hlth, Hlth Educ Div, Taipei, Taiwan;Kaohsiung Med Univ, Kaohsiung, Taiwan
    日期: 2002
    上传时间: 2010-09-24 14:00:40 (UTC+8)
    出版者: SPRINGER-VERLAG
    摘要: Purpose: Conventional technetium-99m methylene diphosphate whole body bone scan (bone scan) has a high sensitivity but a poor specificity to detect bone metastases. However, positron emission tomography with 18F-2-deoxyglucose (FDG-PET) can offer superior spatial resolution and improved specificity. We have attempted to evaluate the usefulness of FDG-PET for detecting bone metastases in renal cell carcinomas (RCC) and to compare FDG-PET results with bone scan findings. Methods: Eighteen patients were selected for this study with biopsy-proven RCC. They were suspected of having bone metastases and were undergoing bone scan and FDG-PET to detect bone metastases. The final diagnoses of bone metastases were established by operative, histopathological findings or clinical follow-up longer than 1 year by additional radiographs or following FDG-PET/ bone scan findings showing progressive and extensive widespread bone lesions. Results: A total of 52 bone lesions including 40 metastatic and 12 benign bone lesions found on either FDG-PET or bone scan were evaluated. FDG-PET could accurately diagnose all 40 metastatic and 12 benign bone lesions. Bone scan could accurately diagnose only 31 metastatic bone lesions. Diagnostic sensitivity and accuracy of FDG-PET were 100% and 100%, respectively, and bone scan were 77.5% and 59.6%, respectively. Conclusions: Our data suggest that FDG-PET has a higher sensitivity and a better accuracy than that of bone scan to detect bone metastases in patients with RCC.
    關聯: INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH 75(8):569-575
    显示于类别:[醫務管理學系暨碩士班] 期刊論文

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