Spatial analysis of Yersinia pestis and Bartonella vinsonii subsp berkhoffii seroprevalence in California coyotes (Canis latrans)

CMUR > College of Public Health > Graduate Institute of Environmental Medicine > Journal articles > Item 310903500/28880

Please use this identifier to cite or link to this item: http://ir.cmu.edu.tw/ir/handle/310903500/28880

Title:	Spatial analysis of Yersinia pestis and Bartonella vinsonii subsp berkhoffii seroprevalence in California coyotes (Canis latrans)
Authors:	Hoar, BR;Chomel, BB;Rolfe, DL;Chang, CC;Fritz, CL;Sacks, BN;Carpenter, TE
Contributors:	公共衛生學院環醫所;Univ Calif Davis, Sch Vet Med, Dept Med & Epidemiol, Davis, CA 95616 USA;Univ Calif Davis, Wildlife Genet Sect, Vet Genet Lab, Davis, CA 95616 USA;Calif Dept Hlth Serv, Div Communicable Dis Control, Sacramento, CA USA;China Med Coll, Grad Inst Environm Hlth, Dept Publ Hlth, Taichung, Taiwan;Calif Dept Food & Agr, Anim Hlth Branch, Modesto, CA 95358 USA;Univ Calif Davis, Sch Vet Med, Dept Populat Hlth & Reprod, Davis, CA 95616 USA
Date:	2003
Issue Date:	2010-09-24 13:59:09 (UTC+8)
Publisher:	ELSEVIER SCIENCE BV
Abstract:	The protective activity of melanin derived from tea (MDFT) was studied using hydrazine as a DNA-reactive chemical agent. Intra-peritoneal administration of MDFT at the doses of 5 or 20 mg/kg dose-dependently prevented liver toxicity induced by hydrazine in rats. It normalized rises in serum alanine transferase activity and a decrease in the glutathione level in the liver. It also reduced the hepatic malondialdehyde concentration. Monitoring the intensity of chemiluminescence showed that MDFT could prevent the production of free radicals that are generated owing to metabolic transformation of hydrazine. It also prevented the formation 8-hydroxy-deoxyguanosine (8-OH-dG) DNA adducts. The results obtained in vivo and in vitro suggest that MDFT confers marked protection of the liver against hydrazine-induced oxidative toxicity. (C) 2002 Elsevier Science Inc. All rights reserved.
Relation:	PREVENTIVE VETERINARY MEDICINE 56(4):299-311
Appears in Collections:	[Graduate Institute of Environmental Medicine] Journal articles

Files in This Item:

There are no files associated with this item.

Loading...