Phase III study of concurrent chemoradiotherapy versus radiotherapy alone for advanced nasopharyngeal carcinoma: Positive effect on overall and progression-free survival

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Title:	Phase III study of concurrent chemoradiotherapy versus radiotherapy alone for advanced nasopharyngeal carcinoma: Positive effect on overall and progression-free survival
Authors:	Lin, JC;Jan, JS;Hsu, CY;Liang, WM;Jiang, RS;Wang, WY
Contributors:	公共衛生學院公衛系;Taichung Vet Gen Hosp, Dept Radiat Oncol, Taichung 407, Taiwan;Taichung Vet Gen Hosp, Dept Otorhinolaryngol, Taichung 407, Taiwan;China Med Coll, Dept Publ Hlth, Taichung, Taiwan;Hung Kuang Inst Technol, Dept Basic Med, Taichung, Taiwan;Natl Yang Ming Univ, Coll Med, Inst Clin Med, Taipei 112, Taiwan
Date:	2003
Issue Date:	2010-09-24 13:55:22 (UTC+8)
Publisher:	AMER SOC CLINICAL ONCOLOGY
Abstract:	Background/Aims: The aim of our study was to evaluate technetium-99m tetrofosmin SPECT (single photon emission computed tomography) of the chest as a potential non-invasive method to evaluate esophagitis among gastroesophageal reflux disease patients. Methodology: In this study, we used non-invasive radionuclide imaging technetium-99m tetrofosmin chest SPECT to detect and grade esophagitis in 60 patients with gastroesophageal reflux disease. Results: Based on the endoscopic findings according to the Savary-Miller system, the sensitivity, specificity, and accuracy rates of technetium-99m tetrofosmin chest SPECT in detecting esophagitis were 95.2%, 72.2% and 88.3%, respectively. The agreement between the endoscopic and technetium-99m tetrofosmin chest SPECT findings was evaluated and found to be good (kappa: 0.633, p<0.001). Conclusions: Non-invasive technetium-99m tetrofosmin chest SPECT has excellent sensitivity and good accuracy as a screen for esophagitis among gastroesophageal reflux disease patients.
Relation:	JOURNAL OF CLINICAL ONCOLOGY 21(4):631-637
Appears in Collections:	[Department of Public Health] Journal articles

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