The ameliorating effects of cognition-enhancing Chinese herbs on scopolamine- and MK-801-induced amnesia in rats

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 中醫學院 > 中國醫學研究所 > 期刊論文 > Item 310903500/28750

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题名:	The ameliorating effects of cognition-enhancing Chinese herbs on scopolamine- and MK-801-induced amnesia in rats
作者:	Lin, YC;Wu, CR;Lin, CJ;Hsieh, MT
贡献者:	中醫學院中醫所;China Med Coll, Inst Chinese Pharmaceut Sci, Taichung, Taiwan
日期:	2003
上传时间:	2010-09-24 13:44:55 (UTC+8)
出版者:	WORLD SCIENTIFIC PUBL CO PTE LTD
摘要:	Shao-Fu-Zhu-Yu-Tang (SFZYT) is reportedly beneficial to sperm. In this study, we examined sperm acrosomal activity and serum free radical changes to evaluate the possible mechanism of SFZYT. A clinical study evaluated the sperm count and motility in 36 patients with chronic prostatitis before and after treatment for 60 days. The results revealed a significant increase in sperm motility after treatment as evaluated by computer-assisted semen analysis (17.27 +/- 9.00 versus 28.29 +/- 10.00, p < 0.01). An increase in sperm quantity and quality was observed by count and morphology with a high-powered intravital microscope. To gain an understanding of the mechanisms that caused this effect, we assessed sperm acrosin activity levels before (10.6 mu lu/10(6)) and after medication (28.6 mu lu/10(6)) (p < 0.01). The levels of the free radicals was relatively higher before medication, 2144, compared to a normal value of 780 after medication (p < 0.01). In conclusion, SFZYT increased the motility and quality of human semen and this increase is related to an increase in sperm acrosin activity. SFZYT also works as a sperm antioxidant and antiaging agent.
關聯:	AMERICAN JOURNAL OF CHINESE MEDICINE 31(4):543-549
显示于类别:	[中國醫學研究所] 期刊論文

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