Anticonvulsive and free radical scavenging activities of vanillyl alcohol in ferric chloride-induced epileptic seizures in Sprague-Dawley rats

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题名:	Anticonvulsive and free radical scavenging activities of vanillyl alcohol in ferric chloride-induced epileptic seizures in Sprague-Dawley rats
作者:	Hsieh, CL;Chang, CH;Chiang, SY;Li, TC;Tang, NY;Pon, CZ;Hsieh, CT;Lin, JG
贡献者:	中醫學院中醫系;China Med Coll, Sch Chinese Med, Taichung, Taiwan;China Med Coll, Inst Chinese Med Sci, Taichung, Taiwan;Jen Ai Hosp, Dept Internal Med, Taichung, Taiwan
日期:	2000
上传时间:	2010-09-24 13:41:32 (UTC+8)
出版者:	PERGAMON-ELSEVIER SCIENCE LTD
摘要:	In-111-oxine-labelled platelet heart scintigraphy (In-plt) was used to evaluate the activity of left atrial thrombi detected by transoesophageal echocardiography (TEE) in 16 cases of rheumatic heart disease. The effect of anticoagulants on the therapeutic intervention of these patients was evaluated by In-pit and TEE. In-Fit was performed in all patients in serial pre- and post-anticoagulant therapy studies with anterior, 45 degrees left anterior oblique and left lateral views taken daily from the second to sixth day after injection of labelled platelets. After discontinuing anticoagulants for at least 1 week, only nine cases of left atrial thrombi were detected among the 16 cases by initial Ln-plt. After anticoagulants were again used for at least 3 weeks, all nine positive cases became negative on repeat In-pit. These results suggest that the diagnostic sensitivity of In-pit is lower than that of TEE. However, In-plt is more suitable and useful for evaluating the activity of left atrial thrombi after antithrombotic agent therapy and for monitoring the effect of anticoagulant therapy on left atrial thrombi in patients with rheumatic heart disease. ((C) 2000 Lippincott Williams & Wilkins).
關聯:	LIFE SCIENCES 67(10):1185-1195
显示于类别:	[中醫學系暨碩博班] 期刊論文

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