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    題名: Antrodia camphorata polysaccharides exhibit anti-hepatitis B virus effects
    作者: Lee, IH;Huang, RL;Chen, CT;Chen, HC;Hsu, WC;Lu, MK
    貢獻者: 中國醫藥大學;Natl Res Inst Chinese Med, Taipei 112, Taiwan;China Med Coll, Taichung 40421, Taiwan
    日期: 2002
    上傳時間: 2010-09-24 13:39:33 (UTC+8)
    出版者: ELSEVIER SCIENCE BV
    摘要: The purposes of this study were to assess the helpfulness of dual phase Tl-201 thyroid scan for differentiating malignant from benign thyroid lesions in cases of thyroid nodules with equivocal fine-needle aspiration (FNA) biopsy results. In addition, for thyroid nodules with equivocal FNA biopsy results, we try to make a decision analysis model compared the FNA biopsy alone strategy (strategy A) with decision strategy for the assistance of dual phase Tl-201 thyroid scan (strategy B) before diagnostic thyroidectomy as thyroid cancer evaluation strategies for hypothetical cohorts of estimated 17,280 - 29,160 Taiwanese patients/per year with equivocal FNA biopsy results. Based on the findings of surgical histopathology, dual phase Tl-201 thyroid scan sensitivity, specificity, and accuracy were 100%, 90%, and 96%, respectively, in cases of 27 thyroid nodules with equivocal FNA biopsy results. In cost effectiveness analysis, the strategy B showed a cost saving of 16,340,480 -27,574,560 US dollars in unnecessary diagnostic thyroidectomy cost. The total cost of strategy B showed a cost saving of 13,932,232 - 23,520,564 US dollars than that of strategy A. The preliminary data indicate that dual phase Tl-201 thyroid scan can save the cost of unnecessary diagnostic thyroidectomy in Taiwanese patients with equivocal FNA biopsy results. In addition, we may provide a noninvasive diagnostic method-dual phase Tl-201 thyroid scan, as the first priority for Taiwanese patients with equivocal FNA biopsy before diagnostic thyroidectomy under the coverage of the national health insurance system in Taiwan.
    關聯: FEMS MICROBIOLOGY LETTERS 209(1):63-67
    顯示於類別:[中國醫藥大學] 期刊論文

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