We reported a 59-year-old man who had been treated for a rectal adenocarcinoma in May 2005 and also received wedge resection of a solitary metastasis in the left upper lung by video-assisted thoracoscopic surgery (VATS) in September 2008. He underwent FDG-PET/CT scanning in August 2009 due to elevating tumor markers. An FDG-avid lesion was found in the muscles of the left lateral chest wall. Physical examination revealed a palpable nodule just beneath the port-site of VATS. Excisional biopsy confirmed this lesion to be metastatic adenocarcinoma of colorectal origin, considered secondary to tumor cell implantation during previous VATS excision of a metastasis.