Ga-67 citrate is bound mainly to transferrin after intravenous injection. The exact mechanism of Ga-67 citrate entry into various tissues is still unknown, but it is thought to be an exchange of transferrin-bound Ga-67 with lactoferrin. The mechanisms of Ga-67 citrate localization in infection and tumor are also controversial and not well understood. Ga-67 citrate has been used widely to localize a variety of infectious lesions. However, the use of Ga-67 citrate to detect ventriculoperitoneal (VP) shunt infection has not been reported previously. Here the authors describe an interesting case of VP shunt infection that was revealed by Ga-67 citrate scintigraphy.
