Application of the electronic nose for uremia diagnosis

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 台中附設醫院 > 會議論文 > Item 310903500/27161

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题名:	Application of the electronic nose for uremia diagnosis
作者:	Lin, YJ;Guo, HR;Chang, YH;Kao, MT;Wang, HH;Hong, RI
贡献者:	附設醫院 Ind Technol Res Inst, Ctr Biomed Engn, Hsinchu, Taiwan;China Med Coll Hosp, Taichung, Taiwan;Natl Taiwan Univ, Dept Agr Chem, Taipei, Taiwan
日期:	2001
上传时间:	2010-09-20 13:55:02 (UTC+8)
出版者:	ELSEVIER SCIENCE SA
摘要:	Breath analysis provides a way to diagnose diseases by detection of special odors in breaths; one of its clinical applications, electronic nose, has been proved as a non-invasive and rapid tool for diagnosis. In this study, a sensor module of the electronic nose is devised with six 12 MHz AT-cut quartz crystals array. probe peptides are designed with structure-based computer simulation, in which a simulated three-dimensional structure of the olfactory receptor protein (ORP) is docking with target gas molecules, and then synthesized. In the clinical test, this sensor module discriminates breaths from the normal subjects, patients with uremia, patients with chronic renal insufficiency (CRI) and patients with chronic renal failure (CRF) well by the discriminating analysis with a correct classification of 86.78%. In general, the normal subjects can be distinguished completely from the patients. (C) 2001 Elsevier Science B.V. All rights reserved.
關聯:	SENSORS AND ACTUATORS B-CHEMICAL 76(1月3日):177-180
显示于类别:	[台中附設醫院] 會議論文

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