中國醫藥大學機構典藏 China Medical University Repository, Taiwan:Item 310903500/2622
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    题名: Nosocomial Outbreak of Infection With Multidrug-Resistant Acinetobacter baumannii in a Medical Center in Taiwan
    作者: 張蕙蘭(Hui-Lan Chang);湯智昕(Tang Chih-Hsin);徐媛曼(Yuan-Man Hsu);萬磊(Lei Wan);張雅棻(Ya-Fen Chang);林炯璁(Chiung-Tsung Lin);曾耀嬬(Yao-Ru Tseng);林應如(Ying-Ju Lin);許晉銓(Jinn-Chyuan Sheu);林振文(Lin Cheng Wen);(Yun-Chieh Chang);何茂旺(Mao-Wang Ho);林嘉德(Chia-Der Lin);何承懋(Cheng-Mao Ho)*;賴志河(Chih-Ho Lai)*
    贡献者: 中國附醫檢驗醫學部微生物科細菌組
    日期: 2009-01
    上传时间: 2009-08-20 17:32:17 (UTC+8)
    摘要: Objective.To investigate a nosocomial outbreak of infection with multidrug‐resistant (MDR) Acinetobacter baumannii in the intensive care units at China Medical University Hospital in Taiwan.

    Design.Prospective outbreak investigation.

    Setting.Three intensive care units in a 2,000‐bed university hospital in Taichung, Taiwan.

    Methods.Thirty‐eight stable patients in 3 intensive care units, all of whom had undergone an invasive procedure, were enrolled in our study. Ninety‐four A. baumannii strains were isolated from the patients or the environment in the 3 intensive care units, during the period from January 1 through December 31, 2006. We characterized A. baumannii isolates by use of repetitive extragenic palindromic–polymerase chain reaction (REP‐PCR) and random amplified polymorphic DNA (RAPD) fingerprinting. The clinical characteristics of the source patients and the environment were noted.

    Results.All of the clinical isolates were determined to belong to the same epidemic strain of MDR A. baumannii by the use of antimicrobial susceptibility tests, REP‐PCR, and RAPD fingerprinting. All patients involved in the infection outbreak had undergone an invasive procedure. The outbreak strain was also isolated from the environment and the equipment in the intensive care units. Moreover, an environmental survey of one of the intensive care units found that both the patients and the environment harbored the same outbreak strain.

    Conclusion.The outbreak strain of A. baumannii might have been transmitted among medical staff and administration equipment. Routine and aggressive environmental and equipment disinfection is essential for preventing recurrent outbreaks of nosocomial infection with MDR A. baumannii.
    關聯: INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY 30(1):34~38
    显示于类别:[台中附設醫院] 期刊論文

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