An Efficient One-Pot Synthesis of N-(1,3-Diphenyl-1H-Pyrazol-5-yl)amides

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题名:	An Efficient One-Pot Synthesis of N-(1,3-Diphenyl-1H-Pyrazol-5-yl)amides
作者:	蘇威年(Su, W.-N.)、林宗平、鄭光閔(Cheng, K.-M.)、(ung, K.-C.)、(Lin, S.-K.)、翁豐富(Wong, Fung Fuh)*
贡献者:	藥學系
日期:	2010-07
上传时间:	2010-08-24 10:14:32 (UTC+8)
摘要:	A “one-pot” method for the synthesis of N-(1,3-diphenyl-1H-pyrazol-5-yl)amides was developed by cyclization of benzoylacetonitrile (1) and phenylhydrazine in neat condition followed by acylation. The corresponding N-(1,3-diphenyl-1H-pyrazol-5-yl)amides were provided in good to excellent yields (70–90%). The significant advantages of the new synthetic method are excellent yields and simple work-up procedure without isolation and purification of intermediary 5-amino-1,3-diphenyl pyrazol (2). J. Heterocyclic Chem., (2010).
關聯:	JOURNAL OF HETEROCYCLIC CHEMISTRY 47(4):831~837
显示于类别:	[藥學系暨碩博士班] 期刊論文

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