The implementation of GHS (Globally Harmonized System of Classification and Labeling of Chemicals) is the international trend, and Taiwan will implement GHS in 2008. In the implementation of GHS, the hazard classification of mixtures is the key step. The flash point value of liquids is the primary parameter in hazard classification for flammable liquids. If a flash point prediction model for mixtures is developed, the flash point of mixtures can be estimated rapidly and economically, and it is helpful in the promotion of GHS. The problem of classification of flammable liquids will be faced in 2008 in Taiwan, and it is urgently and immediately necessary to be resolved. This project is a three-year project. The purpose of this project here is to give a solution for the estimation of flash point for mixtures, the necessity for classification of flammable liquids. Thus, the first year project will aimed at the review and prediction-capability comparison for the flash point prediction models in the literatures. The developments of a prediction model for binary mixtures, which include constitute only with flammable solvents and aqueous-organic solutions, with no additional parameters is the purpose of the next year. The third year will aim at the prediction model for multiple component mixtures. In addition to the academic value, the result of this project can be applied to help the government and industries to promote the implementation of GHS.