蕹菜籽抗細胞增殖活性成分之研究; Studies on Antiproliferative Constituents of the Seeds of Ipomoea aquatica Forsk.

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Title:	蕹菜籽抗細胞增殖活性成分之研究;Studies on Antiproliferative Constituents of the Seeds of Ipomoea aquatica Forsk.
Authors:	鄭雍怡;yung yi cheng
Contributors:	中國醫藥大學藥物化學研究所
Keywords:	蕹菜籽;Ipomoea aquatica Forsk.
Date:	2005
Issue Date:	2010-01-20 16:55:45 (UTC+8)
Abstract:	蕹菜，學名Ipomoea aquatica Forsk.，是臺灣及中國常見蔬菜。現今研究指出，蕹菜預防高血壓、流鼻血的作用及有抑制前列腺素生合成；其水溶性萃取物有降血糖之功效。雖然已經有20餘種成分已經被證實存在蕹菜葉部、根部及地上部分。本研究由蕹菜籽甲醇抽出物以正己烷、乙酸乙酯及氯仿抽取的劃分層進行分離及純化，目前共單離出五個化合物及一個混合物：methyl linoleate (Ⅰ)、oleic acid (Ⅲ)、6-methoxy-7-linoleoxycoumarin (Ⅳ)、β-sitosterol-3-O-D-glucoside (Ⅴ)、化合物Ⅵ及methyl linolenate及ethyl linolenate之混合物 (Ⅱ)。; Water convolvulus, Ipomoea aquatica Forsk., is a popular green vegetable grown in Taiwan and China. It is a delicacy in Chinese cuisine. The studies on the medicinal aspects of this plant include the inhibition of prostaglandin synthesis effects and elimination of constipation . And, it has been well documented that increased eating of water convolvulus is protective against high blood pressure and nose-bleeding. Although more than 20 compounds had been isolated from this plant, further studies of the plant were limited to the aerial part and roots. As the result of the study, five compounds and one complex compounds, that including methyl linoleate (Ⅰ), oleic acid (Ⅲ), 6-methoxy-7-linoleoxycoumarin (Ⅳ), β-sitosterol-3-O-D-glucoside (Ⅴ), compound Ⅵ and methyl linoleate complexes with ethyl linoleate (Ⅱ) has been isolated and subjested to activity investigation.
Appears in Collections:	[Graduate Institute of Pharmaceutical Chemistry] Theses & dissertations

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