本論文在研究無縫膠囊之設備與製程。無縫膠囊為外形圓潤且表面無接縫之球體。以明膠、蠟或可可脂等，做為殼膜之材料，可包覆油性及水性之液體，對於製劑之製造有很大之方便性。研究溶液流速、溶液濃度、溶液種類、冷卻液液面與噴嘴之距離、冷卻液溫度、冷卻液組成、冷卻液體積及噴嘴大小等參數，對於無縫膠囊製備之影響。並對包水無縫膠囊之包覆性做初步性之研究。 無縫膠囊在食品、化妝品、健康食品、藥品之產品中，可因包覆內容物、溶解條件及外觀等需求，做適當之調校，深具開發應用之潛力。; This study was focused on the design of equipments and processes for preparation the seamless capsules. The capsule was made of gelatin, wax, cocoa butter, or their mixtures. The manufacturing process was simple and easy. These capsules can encapsulate liquids, either oil or water solution. In the manufacturing process, the parameters were studied as: the flow speed of outer and inner material solutions, the solution concentrations and compositions, the distance between orifice and level of gelling solutions that a capsule traveled in air, as well as the temperatures, volumes and the compositions of gelling solutions. The size of the outer and inner orifices greatly influenced the size of seamless capsules. These seamless capsules could be used to encapsulate liquid solutions either oil or water. The physical properties of them such as contents and disintegration, appearance, weight variation, size, and stability were investigated. Use these seamless capsules to encapsulate aqueous solutions were the advantages in this study. The technique could be applied to food, cosmetics, and drugs product.
