中國醫藥大學機構典藏 China Medical University Repository, Taiwan:Item 310903500/24605
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    Please use this identifier to cite or link to this item: http://ir.cmu.edu.tw/ir/handle/310903500/24605


    Title: 紅腺忍冬葉部之化學成分研究;Studies on the Chemical constituents of the Leaves of Lonicera hypoglauca MIQUEL
    Authors: 江雯怡;Wen-Yi Chung
    Contributors: 中國醫藥大學中國藥學研究所
    Keywords: 忍冬;紅腺忍冬;長鏈烷類;三?;黃酮;Jen-Tung;Lonicera hypoglauca;alkanes;triterpenoids;biflavonoid
    Date: 2004
    Issue Date: 2010-01-20
    Abstract: 忍冬藥用歷史悠久，為常用的清熱解毒藥，具有抗病原，微生物、消炎、保肝、止血、免疫調節、降血脂、中樞興奮等作用。 紅腺忍冬分佈於大陸、日本、琉球及臺灣。有關紅腺忍冬之化學成分及藥理作用，臺灣尚未見任何報導，因此本研究進行此植物葉部之化學成分分離及鑑定。 紅腺忍冬葉的正己烷及乙酸乙酯抽出物，利用層析法分離，共分離出7個化合物，包括4個長鏈烷類，2個三?類和1個黃酮類，經由各種光譜分析鑑定為： tritriacotane (I)、tetratriacontanoic acid (II)、4-decanol (III)、4-nonacosanol (IV)、3-acetyl oleanolic acid (V)、rhusflavone (VI)、ursolic acid (VII)。而3-acetyl oleanolic acid (V)與rhusflavone (VI)為首次從忍冬屬植物中分離得到。; Jen-Tung has a long medical history for its antipyretic and detoxicating effect. Its actions are antibiotic, anti-inflammatory, heptoprotective, anti-bleeding, immunoregulation, antilipemic, and central exciting etc. Lonicera hypoglauca MIQUEL is distributed in China, Japan, Taiwan and Okinawa. Its chemical constituents and pharmacological effects have never been studied at all in Taiwan. This study deals with the investigation of the chemical constituents of the leaves of this plant. Seven compounds were isolated from hexane and ethyl acetate extracts of the leaves of Lonicera hypoglauca, including four alkanes, two triterpenoids, and one biflavonoid. On the spectroscopic analysis, they were identified as tritriacotane (I), tetratriacontanoic acid (II), 4-decanol (III), 4-nonacosanol (IV), 3-acetyl oleanolic acid (V), rhusflavone (VI), ursolic acid (VII). Among these 3-acetyl oleanolic acid (V), rhusflavone (VI) were the first reported from the genus of Lonicera.
    Appears in Collections:[Graduate Institute of Chinese Pharmaceutical Science] Theses & dissertations

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