中藥穴位貼敷治療過敏性鼻炎臨床療效評估; Acupoint Herbal patch for Allergic rhinitis : A Randomised controlled trial

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Title:	中藥穴位貼敷治療過敏性鼻炎臨床療效評估;Acupoint Herbal patch for Allergic rhinitis : A Randomised controlled trial
Authors:	許維宏;Wei-Hung Hsu
Contributors:	中國醫藥大學中國醫學研究所
Keywords:	過敏性鼻炎;穴位貼敷;ECP;SF-36;Allergic rhinitis;Herbal-patch;ECP;SF-36
Date:	2004
Issue Date:	2010-01-20
Abstract:	隨著環境與生活習慣的改變，全球的氣喘、過敏性鼻炎患者有逐年升高的趨勢。本試驗想要評估中藥穴位貼敷療法對過敏性鼻炎患者血清免疫球蛋白T-IgE、嗜伊紅性陽離子蛋白(Eosinophil cationic protein, ECP)值的變化及對生活品質量表(Short Form-36, SF-36)、鼻炎症狀量表(Rhinitis symptom rating scale, RS)的影響。本試驗採隨機、單盲、平行、對照的實驗設計。在佛教大林慈濟醫院耳鼻喉科、中醫科成立過敏性鼻炎特別門診，篩選合乎納入標準者42人進行臨床試驗，完成試驗者33人。本研究的介入方式為中藥消喘膏穴位貼敷，一週一次，一次三小時，共貼六週。收先將納入試驗的病人隨機分為A、B兩組。A組20人為對照組，在背部穴位上貼澱粉，15人完成；B組為實驗組22人，在背部相同穴位上貼中藥膏，18人完成。每位病患一次貼藥三個小時，一周一次，三次為一療程。預計進行二個療程，每個療程結束皆要填寫問卷，評估療效。二個療程結束後每位病患回診抽血檢測血清T-IgE及ECP值。并填寫問卷(鼻炎症狀量表、SF-36)。結果顯示中藥穴位貼敷對過敏性鼻炎患者的臨床症狀有顯著的治療效果，尤其是對於打噴嚏(p=0.001)、流鼻水(p=0.004)及鼻子癢(p=0.047)等臨床上常見的症狀效果特別顯著。若是以生活品質量表的8個構面來評估療效的話，可見到此種療法對患者的一般健康狀況(p=0.010)及生活的活力(p=0.013)皆有明顯的幫助。關鍵字：過敏性鼻炎；穴位貼敷；ECP；SF36; According to the change of life style and environment, people with allergic rhinitis and asthma are increasing rapidly. This research is an attempt to study the change of T-IgE、ECP、SF-36 and Rhinitis scores for participants with allergic rhinitis treatrd with Herbal point-patch. A single blind, randomize, placebo-controlled and parallel designs were employed in research. 43 eligible participants were screened from outpatient of ENT and Chinese medicine in Da-lin Buddhist Tzu-chi General Hospital. There were 33 eligible participants who had completed the research. . Participants used Chinese herbal point-patch once a week, for 3 hours each time. The treatment cycle was 3 weeks in duration. There were two treatment cycles for each participant. Participants were randomly assigned to two groups: a control group (reference group) and an experimental group. After each cycle was done, a questionnaire was given to the participants to assess the effectiveness of the treatment. At the end of two cycles, each participant was asked to return to the OPD to check for blood serum (T-IgE、ECP) and fill out the questionnaire (Rhinitis severity assessment、SF-36). The data reveal the utility of using the point-patch for the allergic rhinitis, especially with symptoms of sneeze (P=0.001), running (P=0.047) and nose itching (P=0.047). Through the SF-36’s 8 items , the result indicates distinct improvement in GH (general health,P=0.010) and VT (vitality,P=0.013). Keywords：Herbal point-patch ；Allergic rhinitis； ECP；SF36
Appears in Collections:	[Graduate Institute of Chinese Medical Science] Theses & dissertations

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