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    題名: 以心率變異性分析探討針刺與自律神經功能;The Relationship between Acupuncture and Autonomic Nerve Function by Using Heart Rate Variability Analysis
    作者: 劉定明;Liou Ding-Ming
    貢獻者: 中國醫藥學院中國醫學研究所
    日期: 1990
    上傳時間: 2009-12-02 11:48:11 (UTC+8)
    摘要: 首先使用心率變異性(Heart Rate Variability)分析測試31名健康男女,以探討在無針刺下,採用臨床針灸常用之仰躺臥姿。並分別觀察平躺5分鐘後、平躺22分鐘後、平躺32分鐘後、平躺48分鐘後等四個不同時間中,其自律神經的變化為何。結果顯示(1)心率、RR間期平均值、RR間期標準差、相鄰RR間期差大於50 ms的個數佔總RR間期個數的百分比、總功率、低高頻功率比、極低頻頻峰、極低頻功率、低頻頻峰、低頻功率、正規化低頻、高頻頻峰、高頻功率、正規化高頻、低頻最大功率、高頻最大功率等變項,在不同時間階段中有明顯差異性存在。(2)心率隨著時間的增加而呈遞減的變化,而RR間期平均值、RR間期標準差、相鄰RR間期差大於50 ms的個數佔總RR間期個數的百分比、總功率、低頻功率、低頻最大功率、高頻最大功率等則是隨著時間的增加而呈遞增的變化。 另外利用心率變異分析法測試三十一名健康男女,以探討在無針刺、針刺太衝穴、針刺內關穴等三種不同處理時針刺與自律神經的關係。實驗結果顯示在處理和時間交互作用中,僅有高頻功率方面有明顯差異性存在,且是經針刺內關穴後,在取針後十分鐘變異情形是最大。另外在時間因子上,心率、RR間期平均值、RR間期標準差、相鄰RR間期差大於50 ms的個數佔總RR間期個數的百分比、總功率、極低頻頻峰、極低頻功率、低頻功率、高頻功率、低頻最大功率、高頻最大功率等變項有顯著的差異性存在。 最後採用心率變異性(HRV)短時頻域分析法檢測三十名健康男女,在無針刺與針刺非穴位兩種處理中,分別觀察針刺前、針刺後10分鐘、針刺後20分鐘、取針後10分鐘等不同時間,兩種處理對自律神經的影響為何。結果顯示,在不同時間中,有心率、RR間期平均值、RR間期標準差、相鄰RR間期差大於50 ms百分比、總功率、極低頻功率、低頻頻峰、高頻功率、高頻最大功率等變項有明顯差異性存在。而在處理間及處理與時間交互作用中,各種變項則無明顯差異性存在。 實驗結果提示我們,由於長時間平躺就會使心率變異性產生變化,故在研究針灸對自律神經之影響時,時間是一個必須控制的因子。而利用心率變異性分析可直接觀察針刺對自律神經的影響為何,並且可作為臨床療效評估及配穴的依據。而針刺內關穴對副交感神經活性具有提高的作用,至於針刺非穴位對自律神經的影響則較不明顯。; In this study, we use Heart Rate Variability analysis to test 31 healthy adults in order to investigate the change of autonomic activity in those who accept no acupuncture but rest on bed. We observed the change of autonomic activity separately after 5 minutes, 22 minutes, 32 minutes and 48 minutes. The results indicate: (1) these varieties, heart rate, mean value of the RR interval, standard deviation of the RR interval, Ratio LF/HF, pNN50, total power, the peak of the VLF range, the power in the VLF range, the peak of the LF range, the power in the LF range, LF power in normalized units, the peak of the HF range, the power in the HF range, HF power in normalized units, the maximum power in the LF range and the maximum power in the HF range, existed significant variation in different time course. (2) Heart rate decreased with the time increased. These varieties, mean value of the RR interval, standard deviation of the RR intervals, pNN50, total power, the power in the LF range, the maximum power in the LF range and the maximum power in the HF range, increased with the time increased. The second research is to investigate the relationship between acupuncture and autonomic nerve in three groups, non-acupuncture, acupuncture Neiguan (PC6) and acupuncture Taichong (LR3), 31 healthy adults were tested by heart rate variability (HRV) analysis. The interaction between the treatment and the time factor, only the power in the high frequency range existed significant variation, especially after 10 minutes of finished the acupuncture of PC6. Otherwise, considering the time factor, these varieties, heart rate, mean value of the RR interval, standard deviation of the RR interval, pNN50, total power, the peak of the VLF range, the power in the VLF range, the power in the LF range, the power in the HF range, the maximum power in the LF range and the maximum power in the HF range, have significant variation. The third research is to investigate the influence of the autonomic nerve in different treatment, non-acupuncture and non-acupoint acupuncture(1cm next to the Neiguan near the radial side), 30 healthy adults were tested by heart rate variability (HRV) analysis. The results indicate: in different time course, these varieties, heart rate, mean value of the RR interval, standard deviation of the RR interval, pNN50, total power, the power in the VLF range, the peak of the LF range, the power in the HF range and the maximum power in the HF range, existed significant variation. Otherwise, in the different treatment and the interaction between the treatment and the time factor, each variety has no significant variation. The results remind us that according to the change of HRV after resting on bed for a long time, time factor must be controlled in the investigation in the influence of the acupuncture to the autonomic activity. The influence of the autonomic activity can be observed direct
    顯示於類別:[中國醫學研究所] 博碩士論文

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