有兩位患有擴張性心肌病變合併持續性心房顫動的病患在經過電擊整流術,房室結電燒術,及放置心臟再同步化心律調節器後,得到有效的治療。兩位病患罹患持續性心房顫動的時間分別是一週及一年。這項治療不但改善了頑固性的心衰竭,還幫助了心房顫動的控制。第一位病患在11個月的追蹤內未再發生心房顫動,第二位病患在6個月的追蹤內,陣發性心房顫動的發作次數也明顯減少。心房顫動的控制得以進步的機轉可能是由於在放置心臟再同步化心律調節器後,心房之張力及大小減小所造成的結果。
Two patients with dilated cardiomyopathy and persistent atrial fibrillation (AF) underwent successful electrical cardioversion and atrioventricular (AV) junction ablation, followed by implantation of a cardiac resynchronization therapy (CRT) pacemaker with a biventricular pacing system. The duration of persistent AF was one week in patient one and one year in patient two. The interventions resulted in marked improvement in refractory heart failure as well as rhythm control of AF. Patient one was free of AF at 11-month follow-up, and patient two had had markedly fewer episodes of paroxysmal AF during a follow-up period of 6 months. The anecdotal evidence in our two patients suggests that reduction of atrial size and atrial stretch after CRT and hence the atrial anatomical-electrical remodeling is the underlying mechanism for the improvement of rhythm control of AF.