Institute of Environment Health, China Medical University, 91 Hsueh-Shih Road, Taichung 404, Taiwan, ROC. 2 Department of Public Health, China Medical University, 91 Hsueh-Shih Road, Taichung 404, Taiwan, ROC. This case-control study was conducted to analyze the association between single-nucleotide polymorphism of hUART1 (including C258T and C426T) and gout. The study comprised 183 subjects (112 cases and 71 controls) with 48% aborigine and 52% non-aborigine who lived at Ho-Pin area of Taichung County, during January 2005 through November 2006. The hURAT1 genotypes were performed by a PCR-fragment length polymorphism assay. To confirm the genotyping results, selected PCR-amplified DNA samples were examined by DNA sequencing. The proportion of aborigine was higher in case group (60.9%) than in control group (26.5%), (p
