Weaned pigs living group life experience diarrhea caused by different reason. Losses 10-20% due to diarrhea and mortality have been extensive on many of the affected farms.Antibiotics are generally added to animal diets to maintain animal health and prevent diarrhea. We know that abuse of antibiotics increases the emergence of antibiotic resistant bacteria. After livestock consume the feed containing antibiotics, most of the antibiotics return to people and it's is harmful to health. Shen ling bai zhu san, a traditional Chinese prescription medicine, is composed of eleven herbal medicines:fu ling, gan cao, shan yao, bai zhu, ren shen, bai bian dou, jie geng, hong zao, sha ren, lian zi, yi yi ren. Shen ling bai zhu san is commonly used to remedy poor appetite, frequent diarrhea , and emaciation.A study using the prematurely weaned rat as a model for the pig was undertaken to evaluate the effects of Chinese traditional herbal medicine Shen ling bai zhu san. on growth performance ,immune response and hepatorenal function of weaned piglets. Then we utilize above results to investigate the feasibility of replacing antibiotic as growth and health promoter for weaned piglets with the Chinese traditional herbal medicine Shen ling bai zhu san.