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    題名: 知覺干擾與反應衝突對P300的影響;Effect of Perceptual Interference and Response Conflict on P300
    作者: 黃宇詵;Yu-shan Huang
    貢獻者: 中國醫藥大學:醫學研究所碩士班
    關鍵詞: 反應時間;匹配性;一致性;P300潛伏期;Reaction time;congruence;compatibility;P300 latency
    日期: 2007-07-26
    上傳時間: 2009-08-13 14:51:00 (UTC+8)
    摘要: 以事件相關腦電位(Event-related potential, ERP)結合反應時間的時間測量法(chronometry),適用於研究大腦刺激的區辨以及反應選擇的機制。ERP中的P300潛伏期常被用作評估刺激的指標。本研究的目的在探討一致與非一致的視覺刺激(congruence & incongruence visual stimuli)和匹配與不匹配的反應要求(compatible & incompatible reaction time task demand)對於事件相關腦電位(event-related potential, ERP)的影響。研究假定,刺激一致性影響刺激評估期,反應匹配性影響反應選擇期。
    此時間測量模式為利用P300將反應時間再分成兩區段,前半段的P300潛伏期視為刺激評估期(stimulus evaluation);後半段自P300波峰至動作反應之起始點,則視為反應選擇期(response selection)。實驗分二個部份,受試者將在不同組合的實驗情境下交互使用左手或右手作反應,利用一致或非一致的刺激來影響辨識的反應;搭配匹配或不匹配的反應條件要求來影響反應選擇的時間。實驗一採用「箭頭」的空間性刺激符碼,實驗二採用「左右」的語言性刺激符碼。
    實驗一反應時間的結果顯示,刺激一致性與反應匹配性效果顯著,且交互作用明顯,此結果說明,二因素並非分別作用在認知過程的不同階段。事件相關電位的結果顯示,匹配性並不影響反應選擇期,而P300潛伏期的匹配性效果是因刺激型態而異,當一致性刺激時,匹配效果顯著,不一致刺激則否。實驗二的結果,不匹配的文字刺激顯著的増加行為表現的反應時間,和事件相關電位的反應選擇時間;但P300潛伏期不受影響。
    空間性箭頭刺激與文字性刺激,對於本實驗的一致性與匹配性的操控的資訊處理過程是不一樣的。大腦對於一致與不一致的刺激在知覺上或許有不同的解碼以及處理策略,一致性的符碼(code)與動作記憶印象(Engram)之間似乎易形成特殊的鍵結(Bonding)。整個訊息處理過程中匹配性與一致性彼此並非各自獨立、互不干擾。

    Chronometry that combines ERP and reaction time was used to investigate the mechanism of stimulus discrimination and decision execution. The P300 latency is an index of stimulus classification speed. We investigate the effect of congruence visual stimuli and compatibility on ERP and reaction time. We hypothesized that congruency will affect stimulus evaluation and compatibility affect response selection.
    The peak of P300 divided the reaction time into two section. P300 latency is the time for stimulus discrimination;The time from the peak of P300 to the initiation of movement is response selection. Subjects will respond by both hands under different conditions. Ours experiment had two parts. Experiment one used spatial code-「arrow」, experiment two used verbal code-「right & left」.
    The results of experiment one showed that congruency and compatibility have significant effect on reaction time, so is the interaction. The results indicated that the two factors do not affect in parallel at different stages in the cognitive process. ERP results showed that compatibility did not change response selection time, and the effect of compatibility on P300 latency is depended on the congruence of the stimuli. P300 latency shows significant compatibility effect under congruent stimuli. The results of experiment two show that compatibility significantly increased the reaction time, response selection time, but not the P300 latency.
    Brain may code the congruent and incongruent stimuli in different ways during the perceptual process. It seems that a bond may exist between the codes of congruent signals and motor “Engrams” and may affect perception and action planning. This bonding may explain why the P300 latency is longer under incompatible condition while receiving congruency stimulus. Compatibility and congruency are not independent on each other
    顯示於類別:[醫學研究所] 博碩士論文

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