The application of pesticides has increased crop production and quality. However, pesticides can not only caused lethal effects to pests, but also lead to adverse effects to exposed human users and environmental receptors. In order to protect human health and to preserve ecosystem, International Program for Chemical safety of United Nations proposed a framework for integrated risk assessment to efficiently assess human and ecological risk in a simultaneous process. The objective of this year proposal is to assess human and ecological risk for dimethoate and carbaryl. The study subjects include consumers of crops, workers producing these pesticides, and farmers used them. For ecological risk assessment, the most sensitive species will be identified to assess the risk of lethal effects first. Personal sampling will be conducted to assess inhalation and dermal exposures. The concentrations of both pesticides in soil will be sampled and analyzed for modeling the distribution of pesticides in different media for the assessment exposures to the most sensitive species. In the long run, a highly scientific integrated risk assessment will be achieved and pave the way for scientific sound decision-making for dimethoate and carbaryl management.
